TLDR Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
The review article "Pathological sequelae of long-haul COVID" discusses the persistent effects of COVID-19, known as 'post-COVID-19 syndrome' or 'long-haul COVID'. Symptoms can last more than 12 weeks and involve multiple organ systems, regardless of the severity of the initial illness. Common manifestations include fatigue, poor concentration, sleep abnormalities, chronic headache, 'brain fog', memory defects, mood impairment, pain syndromes, cardiac and respiratory issues. Notably, up to 20% of patients may experience persistent hair loss due to acute telogen effluvium, a condition causing diffuse hair shedding after an inflammatory state. The pathophysiology of post-COVID syndrome is not fully understood, but it may be related to a delayed or defective resolution of inflammation, persistent inflammation, induced autoimmunity, and putative viral reservoirs. The review emphasizes the need for detailed profiling of the immune system of patients and the development of new therapeutic targets.
32 citations,
July 2021 in “Journal of The American Academy of Dermatology” Hair loss from COVID-19 usually starts around 45 days after infection and lasts about 47.5 days.
151 citations,
May 2021 in “Frontiers in Medicine” Many patients experience long-lasting symptoms like fatigue and pain after COVID-19, regardless of initial disease severity.
737 citations,
August 2020 in “Journal of Infection” Many COVID-19 survivors experience long-term symptoms but still report satisfactory quality of life and return to work.
70 citations,
January 2015 in “Journal of Clinical and Diagnostic Research” Hair loss from Telogen Effluvium usually gets better within 6 months after addressing the cause.
151 citations,
May 2021 in “Frontiers in Medicine” Many patients experience long-lasting symptoms like fatigue and pain after COVID-19, regardless of initial disease severity.
10 citations,
September 2022 in “Psychiatry and Clinical Neurosciences” Long COVID affects over half of COVID-19 survivors, causing a range of symptoms like fatigue and neurological issues, with no specific treatment yet.
1 citations,
January 2023 in “Revista da Associação Médica Brasileira” Experts agree on the need for standardized definitions and education for post-COVID-19 conditions.
Lower LDL-c levels predict higher COVID-19 mortality.
1250 citations,
August 2021 in “Scientific Reports” COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.
