Oral Dutasteride Is a First-Line Treatment for Frontal Fibrosing Alopecia

    July 2024 in “ Journal of the European Academy of Dermatology and Venereology ”
    Sergio Vañó‐Galván, David Saceda‐Corralo
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    TLDR Oral dutasteride is effective and safe for treating frontal fibrosing alopecia.
    Oral dutasteride is recommended as a first-line treatment for frontal fibrosing alopecia (FFA) due to its effectiveness in stabilizing the condition, as demonstrated in a systematic review and meta-analysis involving 366 patients, where 62.8% achieved stabilization. Despite the lack of double-blind randomized controlled trials, dutasteride shows the highest level of evidence among available treatments. Its potential mechanisms include antifibrotic properties, increased tissue oestradiol levels, and immunomodulatory effects. The treatment is considered safe for off-label use and can be combined with other therapies if needed.
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      in Research/Science  14 upvotes 8 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.
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      in Research  692 upvotes 4 months ago
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      in Chat  10 upvotes 1 month ago
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      in Treatment  6 upvotes 1 month ago
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