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This review traces the development and application of Platelet-rich Plasma in regenerative medicine, emphasizing its role in tissue healing and bone regeneration, but reports no new clinical results.

This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

This study observed that three-dimensional cultures of dermal papilla cells enhanced endothelial cell migration and angiogenesis in vitro, which may improve vascularization in tissue-engineered skin constructs.

In this study, 10 men with androgenetic alopecia who did not respond to standard treatments showed significant hair regrowth and satisfaction after being treated with polydioxanone scalp threads, suggesting a potential therapeutic advantage for this approach.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

Platelet-rich fibrin is becoming popular for medical and cosmetic uses like hair growth and natural fillers.

This review summarizes existing literature on PDGF's role in adipose-derived stem cells, highlighting PDGFRβ's functions in inhibiting white adipocyte differentiation and promoting proliferation and angiogenesis.

This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.

The enzyme PA-PLA1α is important for proper hair follicle development.

This study found that after treatment with platelet-rich plasma, male androgenetic alopecia patients showed significant improvements in hair count, hair diversity, and reduction in certain dermoscopic features.

This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.

This study reports that prenatal and prepubertal exposure to organochlorine compounds and perfluoroalkyl substances may affect pubertal development at age 12, with observed changes in development patterns in both girls and boys, highlighting the need for further research.

This study found that epigallocatechin-3-gallate (EGCG) may reduce paclitaxel-induced apoptosis in human dermal papilla cells by regulating microRNA expression related to apoptosis and cell proliferation.

This study found that coadministration of tadalafil and finasteride improved lower urinary tract symptoms and erectile function in men with benign prostatic hyperplasia better than finasteride alone over 26 weeks.

This study developed a multifunctional 3D-printed hydrogel scaffold, SH-EGCG, that showed promising results for repairing infected diabetic wounds; in lab and animal tests, it demonstrated antibacterial activity, enhanced wound healing, and improved tissue regeneration and remodeling through various supportive mechanisms.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

This study found that a structured teaching program significantly improved adolescent girls' knowledge of polycystic ovary syndrome.

This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.

This study found that freeze-dried homologous platelet-rich plasma (FD HPRP) increased osteocalcin levels in cultured osteoblasts, suggesting its potential to support bone regeneration in periodontal treatment.

This study found that Platelet Rich Plasma is effective as a direct pulp capping agent, comparable to Mineral Trioxide Aggregate, but with potentially better cellular dentinogenic responses and homogenous tissue formation in dogs.

This study found that BBS7 is important for Sonic hedgehog signaling activity, which may be crucial for maintaining periodontal ligament homeostasis in occlusal hypofunction.

This article discusses the potential benefits of platelet-rich plasma injections in ovarian tissue to improve reproductive outcomes in IVF for older individuals and proposes a mechanism to enhance embryo ploidy rescue, but reports no new clinical results.

This study found that increased Bcl-2 protein expression after DPCP treatment was associated with hair regrowth in alopecia areata patients, suggesting its role in inhibiting apoptosis.

This study observed that reduced in utero exposure to the neurosteroid allopregnanolone increased anxiety-like behavior in female guinea pigs during the juvenile period without affecting long-term allopregnanolone levels.

This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.

This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.