TLDR Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.
The document reviews the use of platelet-rich plasma (PRP) in regenerative dentistry, noting its potential for promoting tissue regeneration through the delivery of growth factors and cytokines. PRP has been used in various dental procedures with mixed results; some studies report significant benefits, particularly in endodontic healing, periodontal regeneration, and oral and maxillofacial surgery, while others find no significant effects. The effectiveness of PRP is influenced by the concentration of platelets, with optimal levels required for stimulating cell proliferation, yet higher concentrations may be detrimental. The review calls for standardized PRP preparation protocols and more randomized controlled trials to determine its long-term benefits. It also points out the variability in commercial PRP systems and the need for further research to confirm PRP's clinical advantages in dental regenerative medicine. The document does not specify the number of participants in the studies it references.
87 citations,
March 2020 in “Australian Dental Journal” Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.
53 citations,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
42 citations,
May 2016 in “American Journal of Clinical Dermatology” Using platelet-rich plasma, which is full of growth factors, can help treat pattern hair loss.
119 citations,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
40 citations,
March 2018 in “Aesthetic Surgery Journal” New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
30 citations,
August 2015 in “JAAD case reports” Platelet-rich plasma (PRP) injections successfully treated a woman's steroid-resistant hair loss, causing hair to regrow within a month.
25 citations,
September 2019 in “PubMed” Platelet-Rich Plasma (PRP) is helpful for skin and hair treatments and works better when combined with other procedures.
6 citations,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
3 citations,
December 2023 in “Biomedicines” PRP therapy helps skin heal and improve by promoting cell growth and repair.
2 citations,
January 2014 in “Hair transplant forum international” Platelet Rich Plasma (PRP) therapy can improve hair thinning in male pattern baldness patients, but more research is needed to confirm its effectiveness.