Effects of Diphencyprone on Expression of Bcl-2 Protein in Patients with Alopecia Areata

The study investigated the effects of diphencyprone (DPCP) on the expression of Bcl-2 protein in patients with Alopecia areata. The results indicated that DPCP treatment led to a significant increase in Bcl-2 protein expression in the affected hair follicles. This suggests that DPCP may promote hair regrowth by enhancing the survival of hair follicle cells through the upregulation of Bcl-2, a protein known for its role in inhibiting apoptosis (cell death). The study provided evidence supporting the potential therapeutic use of DPCP in managing Alopecia areata.