Anti-CD44-Mediated Blockade of Leukocyte Migration in Skin-Associated Immune Diseases

    April 2007 in “ Journal of Leukocyte Biology ”
    Margot Zöller, Pooja Gupta, Rachid Marhaba … Pia Freyschmidt‐Paul
    Studysummary This study found that anti-CD44 treatment inhibited leukocyte migration in alopecia areata and eczema, suggesting targeted therapies could enhance contact sensitizer treatment for alopecia areata.
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    Research cited in this study 6

    1. In Vivo CD44-CD49d Complex Formation in Autoimmune Disease Has Consequences on T Cell Activation and Apoptosis Resistance European Journal of Immunology · 2006
    2. A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata Journal of Investigative Dermatology · 2006
    3. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005
    4. Chronic Delayed-Type Hypersensitivity Reaction as a Means to Treat Alopecia Areata Clinical & Experimental Immunology · 2004
    5. Alopecia Areata: Treatment of Today and Tomorrow Journal of Investigative Dermatology Symposium Proceedings · 2003
    6. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998