learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research Anti-CD44-Mediated Blockade of Leukocyte Migration in Skin-Associated Immune Diseases 30 citations, April 2007 in “Journal of Leukocyte Biology” Blocking CD44 can reduce leukocyte migration in autoimmune skin diseases.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance 7 citations, January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata 77 citations, June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models 24 citations, January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results 59 citations, September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
community The Cure isn't 5 years away; it's already here. in Research/Science 1005 upvotes 7 months ago PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.