In Vivo CD44-CD49d Complex Formation in Autoimmune Disease Has Consequences on T Cell Activation and Apoptosis Resistance

    October 2006 in “ European Journal of Immunology ”
    Rachid Marhaba, Pia Freyschmidt‐Paul, Margot Zöller
    Studysummary This study found that CD44 and CD49d together enhance signaling pathways in lymphocytes in mice with alopecia areata, influencing their activation and function.
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    Research cited in this study 5

    1. A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata Journal of Investigative Dermatology · 2006
    2. Chronic Delayed-Type Hypersensitivity Reaction as a Means to Treat Alopecia Areata Clinical & Experimental Immunology · 2004
    3. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002
    4. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    5. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994