Search

for
Search:

Did you mean T lymphocyte activation?

GlossaryT cell activation (T lymphocyte activation)

process where T cells respond to specific antigens

T cell activation is the process by which T cells, a type of white blood cell, are triggered to respond to pathogens or infected cells. This occurs when T cells recognize specific antigens presented by other cells, leading to their proliferation and differentiation into effector cells that can directly attack infected cells or help coordinate the immune response.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 1000+ results

research The Pathogenesis of Alopecia Areata in Rodent Models

23 citations, June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

research Immunosuppressive Therapy in Autoimmune Disease: A Review

5 citations, July 1991 in “Irish Journal of Medical Science (1971 -)”

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata

60 citations, September 2015 in “Expert Review of Clinical Immunology”

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

research Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-Mediated Root Sheath Disruption in Advance of Overt Hair Loss

37 citations, November 2003 in “Veterinary pathology”

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures

research Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures

61 citations, September 2010 in “Genomics”

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

View more "lymphocyte activation" in research →

Community Join

3 / 3 results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.