8 citations
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October 2016 in “Experimental dermatology” This paper proposes that the induction of HF-specific neo-antigens by peripheral CD8+ T cells may maintain self-tolerance but could also lead to immunopathology in conditions like alopecia areata.
February 2018 in “Trends in Immunology” This study demonstrated that antigens from the skin bacterium Staphylococcus epidermidis can stimulate CD8+ T cells, which in turn enhance wound healing.
July 2023 in “International Journal of Trichology” In this case report, a 39-year-old man with sudden whitening of scalp hair due to alopecia areata experienced total regrowth of pigmented hair after six months without systemic treatment.
169 citations
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February 2018 in “Immunity” In this study, researchers found that quiescent stem cells resist immune attack due to downregulated antigen presentation, which may help explain the immune evasion of early cancer-initiating cells.
147 citations
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November 2020 in “International Journal of Molecular Sciences” This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.