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    Glossary Antigen-Presenting Cells

    help activate T-cells by displaying foreign antigens

    Antigen-Presenting Cells (APCs) are a type of immune cell that helps the body recognize and fight off pathogens. They capture antigens (foreign substances) and present them on their surface to T-cells, which then initiate an immune response. Examples of APCs include dendritic cells, macrophages, and B cells.

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    1. Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice 2008 · 119 citations
    2. A Chronic Contact Eczema Impedes Migration of Antigen-Presenting Cells in Alopecia Areata Journal of Investigative Dermatology · 2006 · 24 citations
    3. Antigen presenting cells in the skin of a patient with hair loss and systemic lupus erythematosus. PubMed · 2009 · 9 citations
    4. Targeting of Skin Antigen-Presenting Cells Journal of Animal Science · 2010
    5. Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells Journal of Controlled Release · 2014 · 30 citations
    6. 40nm, but not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells after Transcutaneous Application on Human Skin 2006 · 323 citations
    7. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    8. Follicular transport route – Research progress and future perspectives European journal of pharmaceutics and biopharmaceutics · 2009 · 211 citations
    9. Size-dependent penetration of nanoemulsions into epidermis and hair follicles: implications for transdermal delivery and immunization Oncotarget · 2017 · 96 citations
    10. Delivery and targeting of nanoparticles into hair follicles Therapeutic Delivery · 2014 · 94 citations
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