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GlossaryHLA-DQ

protein complex involved in immune system antigen presentation

HLA-DQ is a protein complex that plays a crucial role in the immune system by helping the body distinguish between its own cells and foreign invaders. It is part of the human leukocyte antigen (HLA) system, specifically involved in presenting antigens to immune cells, which is essential for initiating an immune response. Variations in HLA-DQ genes are associated with susceptibility to certain autoimmune diseases, including type 1 diabetes and celiac disease.

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research Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles

1 citations, September 2023 in “Clinical, cosmetic and investigational dermatology”

Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.

research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle

185 citations, August 2005 in “Autoimmunity Reviews”

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

research Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata

44 citations, December 2005 in “Journal of Investigative Dermatology”

Certain genetic markers, especially the MICA gene, are linked to alopecia areata.

research Analysis of DNA in Hair Fibers

6 citations, March 2003 in “PubMed”

Small amounts of DNA can be found in the hair shaft, especially near the root, but it decreases with hair treatments and washing.

research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review

1 citations, June 2023 in “Genes”

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

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