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GlossaryHLA-DP

part of the immune system that presents antigens to cells

HLA-DP is a part of the human leukocyte antigen (HLA) system, which plays a crucial role in the immune system by helping the body distinguish between its own proteins and those from pathogens. Specifically, HLA-DP is a class II molecule that presents antigens to immune cells, thereby initiating an immune response. This is important in contexts like organ transplantation, autoimmune diseases, and understanding genetic predispositions to certain conditions.

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research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research The Pathogenesis of Alopecia Areata

89 citations, October 1996 in “Dermatologic Clinics”

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

research The Etiology and Pathogenesis of Alopecia Areata

17 citations, July 1994 in “Journal of Dermatological Science”

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

research Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles

1 citations, September 2023 in “Clinical, cosmetic and investigational dermatology”

Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.

Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

research Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

46 citations, April 2016 in “Journal of Investigative Dermatology”

New genes found linked to balding, may help develop future treatments.

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