A 3D-Printed Hydrogel Scaffold Promotes Infected Diabetic Wound Repair via Anti-Inflammation, Angiogenesis, and Extracellular Matrix Remodeling
August 2026
in “
Materials & Design
”
3D-printed hydrogel scaffold SH-EGCG PDA-EGCG nanoparticles EGCG MRSA E. coli fibroblast proliferation angiogenesis macrophage polarization growth factor expression extracellular matrix remodeling epithelial organization matrix organization green tea extract epigallocatechin gallate methicillin-resistant Staphylococcus aureus Escherichia coli
Studysummary This study developed a multifunctional 3D-printed hydrogel scaffold, SH-EGCG, that showed promising results for repairing infected diabetic wounds; in lab and animal tests, it demonstrated antibacterial activity, enhanced wound healing, and improved tissue regeneration and remodeling through various supportive mechanisms.
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