A 3D-Printed Hydrogel Scaffold Promotes Infected Diabetic Wound Repair via Anti-Inflammation, Angiogenesis, and Extracellular Matrix Remodeling

    August 2026 in “ Materials & Design ”
    Yao Wang, Haoming Wu, Yingying Chen … Xulin Hu
    Studysummary This study developed a multifunctional 3D-printed hydrogel scaffold, SH-EGCG, that showed promising results for repairing infected diabetic wounds; in lab and animal tests, it demonstrated antibacterial activity, enhanced wound healing, and improved tissue regeneration and remodeling through various supportive mechanisms.
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    Research cited in this study 2

    1. Exosomes Derived From Mouse Vibrissa Dermal Papilla Cells Promote Hair Follicle Regeneration During Wound Healing By Activating Wnt/β-Catenin Signaling Pathway Journal of Nanobiotechnology · 2024
    2. Human Adipose-Derived Mesenchymal Stem Cells-Derived Exosomes Encapsulated in Pluronic F127 Hydrogel Promote Wound Healing and Regeneration Stem Cell Research & Therapy · 2022