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    Glossary Macrophage Polarization

    process where immune cells change roles based on signals

    Macrophage polarization refers to the process by which macrophages, a type of immune cell, change their functional state in response to different signals in their environment. They can adopt a pro-inflammatory state (M1) to fight infections or a healing state (M2) to repair tissues. This ability to switch roles is crucial for maintaining balance in the immune system and is important in conditions like infections, cancer, and autoimmune diseases.

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    1. Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis Bioactive Materials · 2020 · 61 citations
    2. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022 · 20 citations
    3. Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring Tissue Engineering and Regenerative Medicine · 2024 · 4 citations
    4. CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation Journal of Cellular and Molecular Medicine · 2025 · 3 citations
    5. Human adipose tissue-derived small extracellular vesicles promote soft tissue repair through modulating M1-to-M2 polarization of macrophages Stem Cell Research & Therapy · 2023 · 2 citations
    6. Cedrol from Platycladus orientalis (L.) Franco regulates M1/M2 polarization of macrophages and promotes hair regeneration Journal of Ethnopharmacology · 2026
    7. Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa Frontiers in medicine · 2021 · 22 citations
    8. ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1 Frontiers in Physiology · 2018 · 17 citations
    9. Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation Small · 2022 · 40 citations
    10. Nanofiber-mediated sequential photothermal antibacteria and macrophage polarization for healing MRSA-infected diabetic wounds Journal of Nanobiotechnology · 2021 · 18 citations
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