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    Glossary Macrophage Infiltration

    immune cells moving into tissue, often due to injury

    Macrophage infiltration refers to the process where macrophages, a type of immune cell, move into a specific tissue or area in the body, often in response to injury or infection. These cells help to clear out debris, pathogens, and dead cells, and can also signal other immune responses. In the context of hair and alopecia, macrophage infiltration can influence hair follicle health and potentially contribute to hair loss or regrowth.

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    1. Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages Blood · 2011
    2. Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages Cell reports · 2022 · 6 citations
    3. Implanted hair-follicle-associated pluripotent (HAP) stem cells differentiating to keratinocytes, macrophages and endothelial cells accelerated cutaneous wound closure and suppressed scar formation in a mouse model Research Square (Research Square) · 2022
    4. 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes 2023
    5. Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue International Journal of Molecular Sciences · 2018 · 18 citations
    6. Alterations of collagen type 1, skin fibroblasts, and macrophages in the scalp following the treatment of 1550‐nm erbium glass fractional laser for androgenetic alopecia Journal of Cosmetic Dermatology · 2021
    7. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    8. Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis Annals of Translational Medicine · 2022
    9. The effect of human hair keratin hydrogel on early cellular response to sciatic nerve injury in a rat model Biomaterials · 2013 · 105 citations
    10. Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation Stem Cell Research & Therapy · 2020 · 90 citations
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