Synergistic Antioxidant-Antimicrobial-Immunomodulatory Self-Healing 'Radical Sponge' Hydrogel for Diabetic Wound Regeneration via Microenvironment Reprogramming Mediated by Coordinated MAPK Suppression and PI3K-AKT Activation
March 2026
in “
Chemical Engineering Journal
”
hydrogel dopamine-modified oxidized sodium alginate carboxymethyl chitosan cystamine dihydrochloride basic fibroblast growth factor bFGF reactive oxygen species reactive nitrogen species fibroblast vascular cell epithelialization hair follicle regeneration collagen deposition vascular reconstruction sodium alginate chitosan fibroblast growth factor ROS RNS
Studysummary The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
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