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    GlossaryExtracellular Matrix Remodeling

    continuous restructuring of the protein network outside cells

    Extracellular Matrix Remodeling (ECM Remodeling) refers to the dynamic process where the structure and composition of the extracellular matrix (a network of proteins and other molecules outside cells) are continuously broken down and rebuilt. This process is crucial for tissue development, wound healing, and maintaining healthy skin and hair, but it can also contribute to diseases like fibrosis and cancer if dysregulated.

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      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 4 months ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  36 upvotes 11 months ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

      community Tropoelastin injections + verteporfin?

      in Research/Science  12 upvotes 1 year ago
      The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.