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Glossary Epithelialization

process of new skin cells covering a wound

Epithelialization is the process by which new epithelial cells form and migrate to cover a wound or damaged tissue, creating a protective barrier. This is a crucial step in wound healing, as it helps to restore the integrity of the skin or mucous membranes, preventing infection and further injury.

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research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

13 citations , September 2022 in “Biomolecules”

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

Follicular Dermal Papilla Structures by Organization of Epithelial and Mesenchymal Cells in Interfacial Polyelectrolyte Complex Fibers

research Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers

40 citations , June 2013 in “Biomaterials”

This study developed a 3D engineered hair follicle model that mimics the native hair bulb and may aid in drug screening for hair growth therapies.

research The Epithelial Stem Cell Niche in Skin

9 citations , January 2017 in “Elsevier eBooks”

This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.

research Organizational principles of integumentary organs: Maximizing variations for effective adaptation

8 citations , March 2025 in “Developmental Biology”

Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.

Characterization, Genomic Organization, Expression, and Function of the mEphA1 Receptor Tyrosine Kinase

research Characterisation, genomic organisation, expression and function of the mEphA1 receptor Tyrosine Kinase

April 2007

This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.

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community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling

23 upvotes 10 months ago

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

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