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    GlossaryNF-κB

    protein complex regulating immune response and inflammation

    NF-κB, or Nuclear Factor kappa-light-chain-enhancer of activated B cells, is a protein complex that plays a crucial role in regulating the immune response to infection. It acts as a transcription factor, meaning it helps control the expression of specific genes involved in inflammation, immune response, cell growth, and survival. Dysregulation of NF-κB has been linked to various conditions, including cancer, inflammatory diseases, and autoimmune disorders.

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