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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Olorofim effectively treats fungal skin infections.

Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

M-CSF-stimulated myeloid cells can cause alopecia areata in mice.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Integrin β1 is crucial for liver structure and function, preventing fibrosis.

Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.

Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Lipids from Schizochytrium sp. help prevent hair loss by protecting hair cells from damage and promoting hair growth.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.