Protective Effect of Iris Germanica L. Rhizome-Derived Exosome Against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes
October 2023
in “
Applied sciences
”
Iris germanica L. rhizome-derived exosomes oxidative stress cellular senescence human epidermal keratinocytes reactive oxygen species antioxidant enzyme senescence-associated β-galactosidase cell cycle arrest marker p21 wound-healing properties keratinization markers keratin 1 keratin 10 Iris-exosomes ROS SA-β-gal p21
Studysummary In this study, Iris germanica L. rhizome-derived exosomes were found to reduce oxidative stress, enhance antioxidant enzyme transcription, and restore cellular function in human epidermal keratinocytes, suggesting potential protective effects against oxidative-stress-induced skin damage.
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