1 citations
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May 2024 in “Journal of Pharmacopolium” This review compares nanoemulsion formulas from several plants, such as argan and candlenut oils, which showed enhanced effectiveness in promoting hair growth in animal tests.
July 2026 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, hair tonic formulations containing moringa leaf extract and honey were tested for stability and found to remain stable and non-irritating after storage, meeting specific quality standards.
February 2026 in “Dermatology Reports” This review found that Rosmarinus officinalis (rosemary) leaf extract significantly increased hair density and thickness in patients with androgenetic alopecia, suggesting it may be a promising natural alternative for hair loss treatment with fewer side effects than conventional therapies.
January 2026 in “Journal of Innovative and Creativity (Joecy)” This study investigated hair growth tonics made with celery leaf extract and found that 4% and 9% concentrations maintained better cyclic stability than 14%, supporting their potential use in herbal cosmetic development due to favorable physicochemical stability.
November 2025 in “ACS Omega” This study found that compounds from *Tectona grandis* leaves showed moderate inhibition of steroid 5α-reductase, a factor in androgenetic alopecia, and exhibited anti-inflammatory properties by inhibiting nitric oxide and pro-inflammatory cytokines IL-1β and IL-6 in vitro, suggesting potential dual-action benefits for AGA management.
September 2025 in “Jurnal Ilmu Kedokteran dan Kesehatan Indonesia” The study found that a pomade containing bay leaf extract significantly promoted hair growth in New Zealand White rabbits, with the 30% extract formula demonstrating the highest growth compared to lower concentrations and a control without extract.
August 2025 in “Y HOC TP HO CHI MINH” In this study on Swiss albino mice, researchers reported that perilla leaf extract stimulated hair growth similarly to minoxidil, counteracting hair loss induced by testosterone injections.
This study found that teak leaf extract can be effective in promoting hair growth in males with androgenic alopecia; however, significant variability in steroid 5-alpha reductase inhibitory activity among samples from different geographic origins means quality control is important for consistent therapeutic potential.
June 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” This study observed that using moringa leaf extract in hair tonic reduced hair loss among the sampled students, with the average hair loss decreasing from 118.75 strands to 79.25 strands per day.
April 2025 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, a hair tonic containing fragrant pandan leaf extract and virgin coconut oil was formulated and evaluated, with most variations demonstrating physical stability except for one formulation, which showed instability in the specific gravity test.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.
November 2024 in “Journal of Natural Remedies” This article reviews the use of herbal ingredients in hair care products, highlighting their potential benefits for scalp health, hair growth, and condition, while also discussing challenges such as individual sensitivities and the importance of transparent labeling.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
In this study, clove leaf ethanol extract shampoo at 15% concentration effectively promoted hair growth in male white rats, though it was less effective than 5% minoxidil.
May 2024 in “Jurnal Lmu Farmasi dan Kesehatan/” In an experimental study, researchers evaluated shampoo formulations using celery leaf extract (Apium graveolens L) for hair growth and found that a 2% extract concentration provided the most favorable physical and chemical properties compared to other formulations.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study on rabbits, the authors concluded that a pomade containing 10% meniran leaf extract was an effective hair growth stimulant and could compete with a positive control, fulfilling the required pomade characteristics.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study using male rabbits, researchers found that a 7.5% concentration of green tea leaf ethanol extract hair tonic was nearly as effective in promoting hair growth as the positive control, minoxidil, over a 21-day period.
January 2024 in “Scientific reports” This study found that undiluted mint leaf extract effectively inhibited multidrug-resistant Staphylococcus aureus and killed Culex pipiens larvae, suggesting its potential as a biocontrol strategy around hospitals.
This study found that varying the concentration of propylene glycol in katuk leaf extract hair tonic formulations significantly affects the viscosity, highlighting the importance of propylene glycol concentration in maintaining the physical characteristics of these preparations.
March 2022 in “Journal of drug delivery and therapeutics” Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.
January 2022 in “Lumbung Farmasi: Jurnal Ilmu Kefarmasian/Lumbung Farmasi” In this experimental study, researchers found that a hair tonic combining celery leaf extract and honey, specifically Formula B, showed the highest potential for promoting hair growth in rabbits, with outcomes comparable to a minoxidil control.
This study concluded that bitter melon leaf ethanol extract can be effectively formulated into a shampoo that meets quality standards and promotes rabbit hair growth.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
This study concluded that a shampoo with 10% sodium lauryl sulfate showed the best physical properties among the tested formulas, aligning closely with the Indonesian National Standard.
4 citations
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January 2018 in “Research journal of pharmacy and technology” This study found that Wera leaf extract, particularly its n-hexane fraction, significantly stimulated hair growth, suggesting its potential as an antialopecia treatment.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.
January 2020 in “Archives of Pharmacy Practice” This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.
September 2017 in “Journal of Investigative Dermatology” This study found that stabilizing HIF1A in balding hair follicle cells shifted their metabolism towards glycolysis, reducing oxidative stress and potentially promoting hair growth.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
December 2023 in “Polish Journal of Chemical Technology” This study found that Ajuga reptans leaf and root extracts, when incorporated into cosmetic products, improved skin hydration, elasticity, pore size, hyperpigmentation, and wrinkle depth.