49 citations
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April 2012 in “Phytotherapy Research” This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.
14 citations
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April 2021 in “Heliyon” This study found that both alcoholic and aqueous extracts of Punica granatum L. showed potential for promoting hair growth and exhibited anti-lice and antidandruff activities in a mouse model.
7 citations
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January 2022 in “Brazilian Journal of Biology” This study found that a shampoo formulation using mangabeira leaf extract without sodium lauryl sulfate showed promising antioxidant activity and improved foam quality.
2 citations
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March 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that both bFGF and herbal extracts significantly induced proliferation in human hair follicle mesenchymal stem cells, suggesting their potential for promoting hair growth.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the diverse pharmacological properties and applications of guava leaves, attributing their effectiveness to a rich phytochemical composition and modern extraction techniques, suggesting their potential as natural therapeutic agents across pharmaceutical, nutraceutical, and cosmeceutical fields.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the significant potential of guava leaves as a source of natural therapeutic agents, noting their rich phytochemical content and diverse pharmacological properties, such as antioxidant and anti-inflammatory effects, which may support their application in pharmaceutical, nutraceutical, and cosmeceutical industries.
November 2025 in “Naukovij vìsnik veterinarnoï medicini” This study found that applying aqueous bay leaf extract to skin graft wounds in rabbits reduced inflammation and improved tissue regeneration, leading to enhanced healing compared to untreated controls, particularly in terms of collagen organization, fibrosis, and inflammation modulation over a 21-day period.
January 2022 in “JURNAL BIOSAINS” This study found that a hair tonic made with 10% cassava leaf extract in combination with rose water juice improved hair length growth in rabbits compared to a commercial product.
This study investigated whether combinations of green tea leaf and gotukola extracts could act as a hair growth stimulant but reports no definitive results on the most effective combination.
April 2025 in “Biomacromolecules” This study developed microneedles loaded with Platycladus orientalis leaf extract to treat androgenic alopecia, finding that they can effectively deliver active ingredients into the dermis, promote hair follicle growth by removing free radicals, and activate the Wnt/β-catenin pathway.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.
3 citations
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October 2018 in “International Journal of Green Pharmacy” This study suggested that an herbal shampoo containing Piper betle and Psidium guajava leaves extract may promote hair growth due to its antioxidant properties and showed stability for two months.
128 citations
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September 2003 in “Journal of Ethnopharmacology” This study found that the petroleum ether extract from the leaves of Hibiscus rosa-sinensis demonstrated more effectiveness in promoting hair growth in rats compared to the extract from its flowers.
October 2025 in “Jurnal Medisains Kesehatan” This experimental study found that leaf extracts from Averrhoa bilimbi and Muntingia calabura significantly inhibited the growth of Staphylococcus aureus, with M. calabura demonstrating stronger antibacterial activity, suggesting potential for acne treatment.
14 citations
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July 2017 in “Pakistan Journal of Zoology” Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.
1 citations
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January 2021 in “JIFFK Jurnal Ilmu Farmasi dan Farmasi Klinik” In this study, the researchers found that while the chitosan-alginate gel base supported hair growth, the addition of 0.5% celery extract did not enhance growth, likely due to its low concentration.
June 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This study aimed to create and evaluate a herbal hair serum containing curry leaf and hibiscus extracts, formulated to promote hair growth and reduce hair loss using castor and almond oils as the base.
This study reports the development of a natural hair conditioner incorporating herbs like flaxseed, turmeric, and fenugreek, demonstrating satisfactory physical characteristics, stability, and potential effectiveness as a cost-effective alternative to commercial chemical hair products.
December 2025 in “Jurnal Farmasi Tinctura” This study found that a hair tonic containing 15% ethanol extract of cocoa leaves effectively stimulated hair growth in rabbits, outperforming minoxidil 2%, and was safe with no skin irritation observed.
September 2025 in “International Journal for Research in Applied Science and Engineering Technology” This paper discusses the potential benefits of incorporating guava leaf extracts into skincare, hair care, and oral care products, highlighting their antibacterial, antioxidant, and acne-treating properties, as well as their possible effects on dandruff removal and hair loss reduction.
January 2025 in “Bandung Conference Series Pharmacy” This study found that a solid shampoo containing 15% tin leaf extract (Ficus carica L.) and 1% vitamin E exhibited strong antioxidant activity, with a 53.43% inhibition of free radicals in hair and scalp, suggesting potential for reducing hair loss and premature aging.
June 2024 in “JURNAL BIOLOGI TROPIS” In this systematic literature review, researchers reported that Moringa oleifera Lamk. leaf extract may serve as a potential anti-acne agent, demonstrated by its ability to inhibit the growth of acne-causing bacteria in laboratory settings.
October 2023 in “Indonesian Journal of Biomedicine and Health Science” In this study, researchers found that a combination of celery and candlenut extracts significantly increased hair length in male Wistar rats, while hair weight increased with either extract alone or combined, and hair thickness was most improved with candlenut extract alone.
December 2021 in “Prosiding Seminar Nasional Kesehatan” In this study, the hair tonic made from the ethanol extract of bandotan leaves, applied on local male rabbits for 21 days, demonstrated significant hair growth activity, especially at a 20% concentration, showing the highest hair length and weight improvements.
This study found that ethanolic extract and fractions of Ceiba leaf tonic may enhance rabbit hair growth similarly to 2% minoxidil.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a natural herbal shampoo using extracts from plants like amla and aloe vera, demonstrating effective hair and scalp cleansing, good foaming capacity, and eco-friendliness, aligning with consumer demand for sustainable personal care products.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a natural herbal shampoo using ingredients like amla and aloe vera, finding it effectively cleans hair and scalp, promotes hair growth, and meets eco-friendly personal care product demands, without synthetic additives.
4 citations
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November 2024 in “Nano Biomedicine and Engineering” This study reported that silver nanoparticles synthesized from jackfruit leaf extract demonstrated broad-spectrum antimicrobial properties, with a formulated gel showing greater efficacy against E. coli compared to a commercial silver nitrate product.
3 citations
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August 2019 in “Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan” In this study on New Zealand white rabbits, the researchers reported that a hair tonic formula combining bitter melon leaf and carrot extracts resulted in optimal hair growth, particularly at a 3:1 ratio and a concentration of 3%, without causing irritation.
2 citations
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April 2016 in “Pharmaciana” This study found that a combination of 5% green tea leaf extract and 2.5% gotukola extract stimulated hair growth effectively, achieving a growth rate of 2.689 cm in 28 days.