Guava (Psidium Guajava L.) Leaf Bioactives: From Phytochemical Characterization to Therapeutic and Technological Applications

    Jannatul Firdaus*1, Khushi Rastogi1, Anshika Yadav1, Tanlaka Nuradin Fonyuy1, Shahnawaz Ahmad2
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    Studysummary This review explores the significant potential of guava leaves as a source of natural therapeutic agents, noting their rich phytochemical content and diverse pharmacological properties, such as antioxidant and anti-inflammatory effects, which may support their application in pharmaceutical, nutraceutical, and cosmeceutical industries.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Guava leaves (Psidium guajava L.) are rich in bioactive compounds such as flavonoids, phenolic acids, tannins, terpenes, alkaloids, essential oils, minerals, and vitamins, which contribute to their potent antioxidant, antimicrobial, anti-inflammatory, antidiabetic, anticancer, and hair growth–promoting effects. This review highlights the phytochemical variability, pharmacological properties, and the impact of genetic and environmental factors on their composition. Advanced analytical tools like HPLC, LC-MS, and NMR are used for precise identification and standardization of these bioactives. Modern extraction methods, including ultrasound-assisted and supercritical fluid extraction, enhance the effectiveness of obtaining these compounds. Guava leaves hold promise as a sustainable source of natural therapeutic agents for pharmaceutical, nutraceutical, and cosmeceutical applications.
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