Valorization of Punica Granatum L. Leaves Extracts as a Source of Bioactive Molecules
February 2023
in “
Pharmaceuticals
”
New to pomegranate? There is a guide in the encyclopedia. Read the guide → Studysummary This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
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This study highlights the potential of pomegranate (Punica granatum L.) leaf extracts as a source of bioactive compounds with significant antioxidant, antimicrobial, and cytotoxic properties. The extracts, particularly those obtained through microwave-assisted extraction (MAE), were rich in phenolic compounds and demonstrated strong antibacterial and antifungal activities, as well as cytotoxic effects against cancer cell lines while maintaining over 70% viability in skin cell lines. Despite some toxicity towards non-tumor liver cells, the extracts showed promise for use in nutraceutical and cosmeceutical applications, suggesting their potential as natural antimicrobial agents and in skin-related products. The study emphasizes the valorization of agricultural by-products like pomegranate leaves for sustainable and value-added applications.