21 citations
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February 2023 in “Pharmaceuticals” This study explores the valorization of pomegranate leaves as a source of bioactive compounds using various extraction techniques. The leaf extracts, rich in gallic acid, (-)-epicatechin, and granatin B, demonstrated significant antioxidant, antimicrobial, and cytotoxic properties, as well as skin-beneficial effects. The extracts showed broad-spectrum antimicrobial activity and cytotoxic effects against cancer cell lines, while maintaining over 70% cellular viability in skin cell lines. These findings suggest that pomegranate leaves could serve as a cost-effective source of functional ingredients for nutraceutical and cosmeceutical applications.
77 citations
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July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
25 citations
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November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.