TLDR Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
The document reviewed cosmeceuticals, which are products with both cosmetic and pharmaceutical properties, and their use in dermatology. It covered a range of ingredients, including antioxidants, growth factors, peptides, and botanicals, and their potential skin health benefits. Antioxidants like vitamins A, B, C, and E were discussed for their roles in skin appearance and health, with vitamin E being well-tolerated orally but potentially causing dermatitis when applied topically. Other compounds such as alpha-lipoic acid, ubiquinone, and idebenone were noted for their antioxidant and skin improvement properties. The document also examined botanical extracts like Coffea arabica, green tea, and pomegranate for their anti-inflammatory and skin health benefits. Polyhydroxy acids were mentioned as effective moisturizers and antioxidants, while hypopigmenting agents like hydroquinone were under review for potential toxicity. The document concluded that while cosmeceuticals can offer benefits, they lack the rigorous testing of pharmaceuticals, and further research is needed to confirm their efficacy and safety.
184 citations,
October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” Sulforaphane from broccoli can help protect skin from sun damage.
120 citations,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
30 citations,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
63 citations,
May 2017 in “American Journal of Clinical Dermatology” People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
134 citations,
December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
February 2024 in “Skin health and disease” Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.
5 citations,
May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
9 citations,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
