Sulforaphane Mobilizes Cellular Defenses That Protect Skin Against Damage by UV Radiation
October 2007
in “
Proceedings of the National Academy of Sciences of the United States of America
”
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Studysummary This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
In 2007, researchers found that sulforaphane (SF), a compound from broccoli sprout extracts (BSE), can protect against UV radiation damage. The study included experiments on mice and a human trial with six participants (three males and three females, aged 28-53), which showed a mean reduction in UV-induced erythema of 37.7%. SF's protective effects were attributed to the activation of protective enzymes rather than UV absorption, and these effects lasted for several days. The study concluded that SF could be a potential strategy for skin cancer prevention, offering long-lasting protection without affecting vitamin D synthesis. The human studies were approved by the Institutional Review Board, and the animal studies complied with guidelines approved by the Animal Care and Use Committee.
