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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

      learn Rosemary

      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

    Research

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      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  32 upvotes 3 weeks ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2448 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 2 years ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.