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research Phase III randomised clinical trial comparing primary surgery versus neoadjuvant chemotherapy in advanced epithelial ovarian cancer with high tumour load (SCORPION trial): Final analysis of peri-operative outcome

294 citations , March 2016 in “European journal of cancer”

This study found that neoadjuvant chemotherapy followed by interval debulking surgery led to better quality of life and lower perioperative morbidity compared to primary debulking surgery in advanced epithelial ovarian cancer patients with high tumor load.

research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors

136 citations , April 2013 in “Clinical Cancer Research”

The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.

research Phase I/II randomized bilateral half-head comparison of topical bexarotene 1% gel for alopecia areata

44 citations , October 2009 in “Journal of the American Academy of Dermatology”

This study reported that 1% bexarotene gel was well tolerated and possibly effective for inducing partial hair regrowth in alopecia areata, but more rigorous trials are needed to confirm its efficacy.

research Formulation and in vitro evaluation of polymeric enteric nanoparticles as dermal carriers with pH-dependent targeting potential

43 citations , July 2016 in “European journal of pharmaceutical sciences”

This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.

research Phase II Evaluation of VDC‐1101 in Canine Cutaneous T‐Cell Lymphoma

28 citations , September 2014 in “Journal of Veterinary Internal Medicine”

This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.

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Community Join

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community Phase 3 Study for PP405 officially posted

43 upvotes 3 days ago

PP405 is in a phase 3 trial for hair loss treatment, with the study expected to run until June 2028. Minoxidil and finasteride remain key treatments, with hopes for PP405 to offer a new mechanism of action.

community Phase 3 for PP405 will now start in 2027

in Chat 81 upvotes 1 month ago

Phase 3 for PP405 will start in 2027, disappointing many who expected it this year. Some users are trying treatments like topical minoxidil and topical dutasteride while waiting for new developments.

community Phase 2B trial for PP405 leaked (The study Pelage DOESN'T want you to see)

5 months ago

The conversation discusses hair loss treatments, mentioning minoxidil, finasteride, RU58841, VDPHL, GT20029, and follicle cloning as potential solutions. It also reveals that the discussion about PP405 was an April Fool's joke.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 7 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

in Research/Science 11 upvotes 2 years ago

The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

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Learn

3 / 801 results

learn Finasteride

Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; an early shedding phase is common and usually temporary. The benefit lasts only while the drug is taken, and it is prescription-only.

learn Hair Transplant

Is shedding normal after a hair transplant? Shedding is normal after a hair transplant and usually resolves within weeks.
How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.
What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

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Experts

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Clinics

2 / 500 results