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This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.

This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.

This study found that hair proteome profiling and genetically variant peptide identification in hairs remained effective after an explosive blast, indicating potential for forensic human identification despite damage.

This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.

This study found that the orally disintegrating tablet and standard tablet formulations of finasteride met bioequivalence criteria in fasting healthy adult male Han Chinese volunteers, although there was a significant difference in time to maximum concentration.

This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.

This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.

This study developed an efficient method for converting polymeric procyanidins into high-purity oligomeric procyanidins using a semisynthetic approach combined with separation techniques.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This research found that ethosomes significantly enhanced finasteride delivery into the dermis of human cadaver skin compared to liposomes in an in vitro study.

This study found that taxol induces apoptosis in dermal papilla cells, affecting protein expression related to biological processes and potentially contributing to taxol-induced alopecia.

This review discusses the limitations of current hair classification systems and highlights the need for standardized reporting of key hair characteristics to improve study comparisons; it reports no new results.

In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

This study found that co-administering glucocorticoids with 5α-reductase inhibitors exacerbated the adverse metabolic effects of glucocorticoids in healthy men.

This study found that post-finasteride syndrome patients showed a tissue-specific methylation pattern of the SRD5A2 promoter in cerebrospinal fluid, potentially affecting neuroactive steroid levels and related behavioral symptoms.

This study found that a gintonin-enriched fraction from ginseng promoted hair growth in mice by stimulating dermal papilla cell proliferation and increasing hair follicles and weight.

This study observed that ethyl glucuronide (EtG) concentrations in hair decreased significantly during an abstinent period, suggesting possible wash-out effects or other factors affecting EtG levels.

This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.

In this review, the authors aim to improve the differential diagnosis between hyperandrogenic PCOS and NCAH, which could lead to more personalized treatment strategies for patients experiencing hyperandrogenism.

In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.

In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.

This study found that protein arginine methylation levels in human hair may correlate with a cardiovascular biomarker in blood, suggesting hair sampling as a potential non-invasive method for cardiovascular risk assessment.

This study reports two cases of fatal metformin intoxication with hair concentrations significantly higher than those in subjects under treatment, marking the first use of hair analysis for such cases.

This study found that recombinant murine IL-36α increased the number of regenerated hair follicles and accelerated wound healing in a mouse model of wound-induced hair follicle neogenesis.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

This study found that dutasteride treatment in pregnant mares significantly increased progesterone concentrations but did not alter gestational length or neonatal outcomes.

In this study, a herbal extract mixture significantly reduced IL-1α gene expression in HaCaT cells, suggesting it may aid in the treatment of nonscarring alopecia.