Promotion of Hair Growth by Newly Synthesized Ceramide Mimetic Compound

July 2017 in “ Biochemical and biophysical research communications ”

Bu‐Mahn Park, Soon‐Sun Bak, Kyung-Oh Shin, Minhee Kim, Dae-Hwan Kim, Sang‐Hun Jung, Sekyoo Jeong, Young Kwan Sung, Hyun Jung Kim

bis-oleamido isopropyl alcohol ceramide mimetic compound hair growth telogen anagen sphinganine sphingosine ceramide dermal papilla cells sphingolipid synthesis BOI telogen phase anagen phase

Studysummary This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.

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