Characteristics of Malassezia Furfur at Various pH and Effects of Malassezia Lipids on Skin Cells

This study investigates the characteristics of Malassezia furfur and its lipid metabolism at various pH levels, focusing on their effects on skin cells. Malassezia species, which lack fatty acid synthesis genes, rely on external lipids and are influenced by skin pH. The research found that at pH 7, Malassezia furfur exhibited low growth and reduced lipid content, negatively impacting skin health. Conversely, at pH 6, lipids bio-converted by Malassezia species positively affected skin cells by regulating inflammation, moisturizing, and promoting elasticity. These findings highlight the importance of studying Malassezia-derived lipids under different pH conditions to understand their potential benefits for skin health.