Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

    January 2021 in “ Pharmaceutics ”
    Hey-Won Shin, Joo-Eun Kim, Young-Joon Park
    Studysummary This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.
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    Research cited in this study 3

    1. Formulation of a Film-Coated Dutasteride Tablet Bioequivalent to a Soft Gelatin Capsule (Avodart): Effect of Gamma-Cyclodextrin and Solubilizers Asian Journal of Pharmaceutical Sciences · 2019
    2. Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery European Journal of Pharmaceutics and Biopharmaceutics · 2017
    3. Dutasteride in Androgenetic Alopecia: An Update Current Clinical Pharmacology · 2017