From Stem Cells Protection to Skin Microbiota Balance: Orobanche Rapum Extract, a New Natural Strategy

The document discusses a study on a new plant extract from Orobanche rapum, aimed at rejuvenating skin by stimulating stem cells and protecting skin microbiota. The study found that the extract maintained the clone-forming capacity of skin stem cells and increased their resistance to UV damage by overexpressing survivin and inhibiting caspases. Additionally, the extract restored epidermal differentiation markers and ceramide biosynthesis, which is beneficial for skin lipid organization. Clinical studies confirmed that the extract not only promoted skin surface renewal but also protected the skin microbiota. The conclusion of the study is that Orobanche rapum extract effectively stimulates skin rejuvenation and microbiota protection, leading to healthier and more beautiful skin.