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GlossarySurvivin

protein that inhibits cell death and regulates cell division

Survivin is a protein that inhibits cell death (apoptosis) and is involved in regulating cell division. It is often found at high levels in cancer cells, making it a target for cancer therapies. In the context of hair and alopecia, its role in cell survival and proliferation could be significant for understanding hair follicle health and regeneration.

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Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin

research Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin

13 citations , August 2020 in “Frontiers in Cell and Developmental Biology”

Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

research Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I

29 citations , January 2016 in “Disease Markers”

Survivin and IGF-I may play a role in acne and scarring.

Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

11 citations , October 2019 in “Cancers”

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going

3 citations , October 2022 in “Frontiers in Surgery”

Proteomics combined with other technologies can lead to a better understanding of skin diseases.

research Expression of Vascular Endothelial Growth Factor, Apoptosis Inhibitors (Survivin and p16) and CCL27 in Alopecia Areata Before and After Diphencyprone Treatment: An Immunohistochemical Study

58 citations , May 2004 in “British Journal of Dermatology”

Diphenylcyclopropenone treatment helps hair growth in alopecia areata by promoting blood vessel growth and cell survival.

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community Failed HT or expected result? 4505 grafts, Eugenix, New Delhi.

in Transplants 36 upvotes 9 months ago

The hair transplant at Eugenix in New Delhi resulted in poor density and texture, with only about 2,500 grafts surviving out of 4,500. The user is considering holding the clinic accountable and exploring options like shaving, using hair fibers, or seeking another transplant.

community 26M, grade 3, 2.5 Oral Mg minoxidil 1MG finasteride , kLM d3 , Minoxidil 5%, ketocinazole shampoo.I will post the pics after every 6 weeks.

in Treatment 16 upvotes 2 years ago

A 26-year-old male with grade 3 hair loss is using 2.5 mg oral minoxidil, 1 mg finasteride, 5% minoxidil, ketoconazole shampoo, and kLM d3. He plans to post progress pictures every 6 weeks and is seeking suggestions.

community Ejaculation and Oxytocin are responsible for Hair loss

7 years ago

The conversation discusses the idea that ejaculation and oxytocin might cause hair loss. It mentions treatments like Minoxidil, finasteride, and RU58841.

community Is it possible to retain minoxidil gains after quitting? Has anyone been able to do that on here? If so, how?

in Treatment 7 upvotes 4 weeks ago

Minoxidil gains are typically lost after stopping its use, but some suggest finasteride or dutasteride might help retain them, though results vary. Microneedling and low-level laser therapy are mentioned as alternative treatments, but minoxidil is noted for having a more significant impact.

community Two transplants later, loads of misinformation & a rollercoaster of a journey I'm finally on the mend.

in Progress Pictures 91 upvotes 2 months ago

A user shared their hair loss journey, detailing two hair transplants and various treatments including finasteride, minoxidil, PRP, and exosomes. They found success with a regimen of topical dutasteride, minoxidil, derma stamping, and caffeine shampoo, leading to improved hair growth and satisfaction.

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