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GlossaryCaspase

enzymes that trigger cell death by cutting specific proteins

Caspases are a family of enzymes that play a crucial role in programmed cell death, also known as apoptosis. They act like molecular scissors, cutting specific proteins in the cell to trigger a cascade of events leading to cell dismantling and removal, which is essential for maintaining healthy tissue and organ function.

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research Caspases in Life and Death: Their Role in Head Formation

7 citations, January 2023 in “Frontiers in Cell and Developmental Biology”

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice

59 citations, September 2015 in “Journal of Immunology”

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

21 citations, January 2002 in “Journal of Cutaneous Medicine and Surgery”

Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.

research From Stem Cells Protection to Skin Microbiota Balance: Orobanche Rapum Extract, a New Natural Strategy

9 citations, November 2018 in “Journal of cosmetic dermatology”

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

research Non-Apoptotic Role for Caspase-7 in Hair Follicles and Surrounding Tissue

6 citations, August 2015 in “Journal of Molecular Histology”

Caspase-7 has functions in skin and hair that are not related to cell death.

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community Hair loss causes are still a myth.

in Chat 16 upvotes 2 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.