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GlossaryCaspase

enzymes that trigger cell death by cutting specific proteins

Caspases are a family of enzymes that play a crucial role in programmed cell death, also known as apoptosis. They act like molecular scissors, cutting specific proteins in the cell to trigger a cascade of events leading to cell dismantling and removal, which is essential for maintaining healthy tissue and organ function.

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research RNase L Represses Hair Follicle Regeneration Through Altered Innate Immune Signaling

February 2025 in “Journal of Clinical Investigation”

RNase L hinders hair growth by altering immune signals.

research Male Androgenetic Alopecia

1 citations, August 2002 in “Zeitschrift für Hautkrankheiten”

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

21 citations, January 2002 in “Journal of Cutaneous Medicine and Surgery”

Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.

research Non-Apoptotic Role for Caspase-7 in Hair Follicles and Surrounding Tissue

6 citations, August 2015 in “Journal of Molecular Histology”

Caspase-7 has functions in skin and hair that are not related to cell death.

research From Stem Cells Protection to Skin Microbiota Balance: Orobanche Rapum Extract, a New Natural Strategy

9 citations, November 2018 in “Journal of cosmetic dermatology”

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

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community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.