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GlossaryCaspase

enzymes that trigger cell death by cutting specific proteins

Caspases are a family of enzymes that play a crucial role in programmed cell death, also known as apoptosis. They act like molecular scissors, cutting specific proteins in the cell to trigger a cascade of events leading to cell dismantling and removal, which is essential for maintaining healthy tissue and organ function.

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research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells

58 citations, January 2006 in “Skin Pharmacology and Physiology”

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

research Apoptosis, Androgenetic Alopecia, and the Hair Cycle

January 2002 in “Hair transplant forum international”

Finasteride reduces hair follicle cell death in androgenetic alopecia.

research The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro

39 citations, July 2007 in “Archives of Pharmacal Research”

A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.

research RNase L Represses Hair Follicle Regeneration Through Altered Innate Immune Signaling

February 2025 in “Journal of Clinical Investigation”

RNase L hinders hair growth by altering immune signals.

research Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/FasL-Mediated Apoptotic Signaling

29 citations, March 2014 in “PloS one”

Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.

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community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.