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GlossaryCaspase-7

enzyme involved in programmed cell death (apoptosis)

Caspase-7, also known as CASP7, is an enzyme that plays a crucial role in the process of apoptosis, which is the programmed cell death essential for maintaining healthy tissue and organ function. It is part of a family of proteases that, when activated, can break down cellular components, leading to the orderly and efficient removal of damaged or unnecessary cells. This process is vital for development, immune system function, and preventing diseases such as cancer.

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research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells

25 citations , December 2008 in “The Journal of Urology”

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

research Non-Apoptotic Role for Caspase-7 in Hair Follicles and Surrounding Tissue

6 citations , August 2015 in “Journal of Molecular Histology”

Caspase-7 has functions in skin and hair that are not related to cell death.

research Caspases in Life and Death: Their Role in Head Formation

7 citations , January 2023 in “Frontiers in Cell and Developmental Biology”

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

research The Abnormal Skin Structure of Newborn Wistar Rats Maternally Treated with Aspartame: Histological and Immunohistochemical Study

May 2016 in “Research opinions in animal & veterinary sciences”

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

research Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro

140 citations , December 1998 in “Journal of Investigative Dermatology”

Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.

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community Hair loss causes are still a myth.

in Chat 17 upvotes 4 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Don't use PP405 from everychem. it is likely fake.

in Research/Science 64 upvotes 8 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.