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GlossaryCaspase-7

Caspase-7, also known as CASP7, is an enzyme that plays a crucial role in the process of apoptosis, which is the programmed cell death essential for maintaining healthy tissue and organ function. It is part of a family of proteases that, when activated, can break down cellular components, leading to the orderly and efficient removal of damaged or unnecessary cells. This process is vital for development, immune system function, and preventing diseases such as cancer.

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research Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue

6 citations , August 2015 in “Journal of Molecular Histology”

Caspase-7 has functions in skin and hair that are not related to cell death.

research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells

25 citations , February 2009 in “The Journal of Urology”

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

research Making the head: Caspases in life and death

7 citations , January 2023 in “Frontiers in Cell and Developmental Biology”

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

The abnormal skin structure of newly born Wistar rat maternally-treated with aspartame: histological and immunohistochemical study

research The abnormal skin structure of newly born Wistar rat maternally-treated with aspartame: histological and immunohistochemical study

May 2016 in “Research opinions in animal & veterinary sciences”

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

25 citations , July 2021 in “Developmental Cell”

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

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community Hair loss causes are still a myth.

in Chat 18 upvotes 2 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.