Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells

    December 2008 in “ The Journal of Urology ”
    Robert B. Bass, Billy Perry, Peter Langenstroer … Jeffrey M. Holzbeierlein
    Studysummary In this study, short-term finasteride treatment reduced apoptotic factors caspase-7 and IGFBP-3 in prostate cancer cells but did not significantly affect androgen receptor expression compared to placebo.
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    Research cited in this study 3

    1. Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle Journal of Cutaneous Medicine and Surgery · 2002
    2. The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1998
    3. PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 1998