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    Glossary Apoptotic Pathway

    process where cells self-destruct in a controlled manner

    The apoptotic pathway, also known as the programmed cell death pathway, is a series of biochemical events that lead to the orderly and efficient elimination of damaged or unnecessary cells. This process is crucial for maintaining tissue health and homeostasis, and it involves the activation of specific proteins called caspases that dismantle the cell from within, ensuring that the cell's contents are safely recycled or disposed of without causing inflammation or damage to surrounding tissues.

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    1. Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways International journal of molecular sciences · 2023 · 3 citations
    2. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    3. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    4. All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway Acta histochemica · 2020 · 10 citations
    5. Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways Cell Proliferation · 2025
    6. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    7. VDAC2 Mediates the Apoptosis of Cashmere Goat Hair Follicle Stem Cells Through the P53 Signaling Pathway Animals · 2025
    8. Caizhixuan hair tonic regulates both apoptosis and the PI3K/Akt pathway to treat androgenetic alopecia PLOS ONE · 2023
    9. Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia Dermatologic Surgery · 2019 · 11 citations
    10. All-trans retinoic acid modulates proliferation and apoptosis of secondary hair follicle–dermal papilla cells in cashmere goats via the TGF-β2/Smad2/3 pathway Frontiers in Veterinary Science · 2026
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    Community 1 of 4

    1. [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression Reddit · 4 Dec 2019
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