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    Glossary JNK pathway

    signaling cascade responding to stress, regulating inflammation and cell death

    The JNK pathway, also known as the c-Jun N-terminal kinase pathway, is a signaling cascade within cells that responds to stress stimuli, such as UV radiation and inflammatory cytokines. It plays a crucial role in regulating various cellular processes, including inflammation, apoptosis (programmed cell death), and cell differentiation. This pathway is significant in understanding diseases like cancer and neurodegenerative disorders, as well as conditions affecting hair growth and alopecia.

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    1. Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK—ERK Signaling Pathway Cell Transplantation · 2013 · 45 citations
    2. Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway Drug Design Development and Therapy · 2025
    3. Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway PLOS ONE · 2011 · 38 citations
    4. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    5. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    6. Co-opting Developmental Signaling Pathways to Promote Wound Healing Recent clinical techniques, results, and research in wounds · 2018 · 1 citations
    7. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    8. Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin- induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress Food Science and Human Wellness · 2026
    9. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    10. sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation Stem cells · 2016 · 9 citations
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    1. Physio-metabolic method (antiandrogen, minoxidil, leg training and cold) Community · 7 Jun 2024
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