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signaling cascade responding to stress, regulating inflammation and cell death

The JNK pathway, also known as the c-Jun N-terminal kinase pathway, is a signaling cascade within cells that responds to stress stimuli, such as UV radiation and inflammatory cytokines. It plays a crucial role in regulating various cellular processes, including inflammation, apoptosis (programmed cell death), and cell differentiation. This pathway is significant in understanding diseases like cancer and neurodegenerative disorders, as well as conditions affecting hair growth and alopecia.

Related Terms

• c-Jun N-terminal kinase
• JAK-STAT pathway
• MAPK pathway
• Janus Kinase
• p38 MAPK pathway
• NF-κB pathway
• Janus Kinase 1
• Janus Kinase 3