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    Glossary JNK pathway

    signaling cascade responding to stress, regulating inflammation and cell death

    The JNK pathway, also known as the c-Jun N-terminal kinase pathway, is a signaling cascade within cells that responds to stress stimuli, such as UV radiation and inflammatory cytokines. It plays a crucial role in regulating various cellular processes, including inflammation, apoptosis (programmed cell death), and cell differentiation. This pathway is significant in understanding diseases like cancer and neurodegenerative disorders, as well as conditions affecting hair growth and alopecia.

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    Research 30 of 706

    1. Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK—ERK Signaling Pathway Cell Transplantation · 2013 · 45 citations
    2. Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway Drug Design Development and Therapy · 2025
    3. Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway PLOS ONE · 2011 · 38 citations
    4. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    5. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    6. Co-opting Developmental Signaling Pathways to Promote Wound Healing Recent clinical techniques, results, and research in wounds · 2018 · 1 citations
    7. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    8. Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin- induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress Food Science and Human Wellness · 2026
    9. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    10. sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation Stem cells · 2016 · 9 citations
    11. Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021 · 14 citations
    12. 446 Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway The Journal of Sexual Medicine · 2018
    13. Integrin β1 Establishes Liver Microstructure and Modulates Transforming Growth Factor β during Liver Development and Regeneration American Journal Of Pathology · 2020 · 10 citations
    14. Microcirculation-Promoting Effect of Escin on Cutaneous Tissue via Gsk3β Down-Regulation Current Issues in Molecular Biology · 2025 · 1 citations
    15. Teatro D. Fernando: um teatro de curto prazo 2014 · 1 citations
    16. Premature aging and cancer development in transgenic mice lacking functional CYLD Aging · 2019 · 16 citations
    17. Context-dependent effect of sPLA2-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer EBioMedicine · 2019 · 13 citations
    18. Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling Frontiers in Bioscience-Landmark · 2026
    19. VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK Experimental Cell Research · 2012 · 120 citations
    20. Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells <i>via</i> Anagen-Activating Signaling Pathways Biological & Pharmaceutical Bulletin · 2018 · 5 citations
    21. Insights into the role of the Wnt signaling pathway in the regeneration of animal model systems The International Journal of Developmental Biology · 2023 · 21 citations
    22. Wnt4 is crucial for cardiac repair by regulating mesenchymal-endothelial transition via the phospho-JNK/JNK Theranostics · 2022 · 11 citations
    23. Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives International Journal of Molecular Sciences · 2024 · 9 citations
    24. USING THE FROG EPIDERMIS TO UNCOVER DESMOSOME FUNCTION AND REGULATION IN THE DEVELOPING EMBRYO VCU Scholars Compass (Virginia Commonwealth University) · 2018
    25. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma Nature Communications · 2020 · 60 citations
    26. Il-10 family members as novel responders to genotoxic stress ScholarlyCommons (University of Pennsylvania) · 2015
    27. Protective Effect of Iris germanica L. Rhizome-Derived Exosome against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes Applied sciences · 2023
    28. The role of <i>Atg5</i> gene in tumorigenesis under autophagy deficiency conditions The Kaohsiung Journal of Medical Sciences · 2024 · 4 citations
    29. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    30. Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways Journal of Cosmetic Dermatology · 2013 · 39 citations