Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

September 2017 in “ Lasers in Surgery and Medicine ”

Jung E. Kim, Young Sup Woo, Ki Min Sohn, Kwan Jeong, Hoon Kang

photobiomodulation therapy LED light human outer root sheath cells hORSCs Wnt/β-catenin pathway ERK signaling pathway human dermal papilla cells hDPCs apoptosis cell proliferation cell migration PBMT LED outer root sheath cells dermal papilla cells

Studysummary This study found that LED light irradiation induced proliferation and migration of human outer root sheath cells, potentially through the stimulation of the Wnt/β-catenin and ERK signaling pathways.

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