Regulatory Processes of the Canonical Wnt/β-Catenin Pathway and Photobiomodulation in Diabetic Wound Repair

    April 2022 in “ International Journal of Molecular Sciences ”
    Sandy Winfield Jere, Nicolette N. Houreld
    TLDR Understanding the Wnt/β-catenin pathway and photobiomodulation could improve diabetic wound healing.
    The document reviewed the role of the canonical Wnt/β-catenin pathway in skin wound repair and explored how photobiomodulation (PBM) could influence chronic wound healing, particularly in diabetic patients. It highlighted that diabetic patients often faced challenges with chronic, non-healing wounds, which could lead to severe complications like limb amputation. PBM, which uses low-powered light to stimulate biological activities, was noted to potentially modulate the Wnt/β-catenin pathway, although its exact role in chronic wound healing was not fully understood. The review emphasized the importance of understanding these signalling pathways to improve wound healing outcomes.
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