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GlossaryHuman Outer Root Sheath Cells (hORSCs)

cells in hair follicle's outer layer aiding growth and regeneration

Human Outer Root Sheath Cells are a type of cell found in the outer layer of the hair follicle. These cells play a crucial role in the growth and regeneration of hair, as they provide structural support and house stem cells that can differentiate into various cell types needed for hair production.

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Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

research Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

43 citations, September 2017 in “Lasers in Surgery and Medicine”

LED light therapy may help hair growth by activating certain cell pathways.

research Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles

14 citations, April 2021 in “International journal of molecular sciences”

Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.

research Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells

13 citations, September 2021 in “Current Issues in Molecular Biology”

Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.

Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative Stress and Regulating Glycogen Breakdown in Human Hair Follicles

research Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative Stress and Regulating Glycogen Breakdown in Human Hair Follicles

August 2024 in “Biomolecules & Therapeutics”

A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.

research AP Collagen Peptides (APCPs) Promote Hair Growth by Activating the GSK-3β/β-Catenin Pathway and Improve Hair Condition

July 2024 in “Experimental Dermatology”

AP collagen peptides help hair grow and improve hair health.

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community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 3 weeks ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community 3 months on minoxidil / derma rolling. Both pictures immediately after shower

in Progress Pictures 389 upvotes 1 year ago

User had good results with minoxidil and derma rolling for hair loss in 3 months. Others suggest adding finasteride to maintain progress.

community Doctors won't let me try bicalutamide or fin

in Female 8 upvotes 3 years ago

Hair loss treatments discussed include 200mg Spiro, bicalutamide, and finasteride. Endocrinologist advises against bicalutamide and finasteride due to potency and risks.

community The worst part of balding is its harder to maintain a balding head

in Shaved/buzzed 327 upvotes 7 months ago

The conversation discusses the challenges of maintaining a balding head, with some preferring to shave regularly and others choosing to embrace their hair loss. Specific treatments or concerns about hair transplants and societal perceptions of balding are also mentioned.

community Tell me I should be grateful, I’m trying not to shave it off. I’ve had about 2500 graft’s transplanted but I hate seeing my scalp.

in Is this regrowth? 101 upvotes 1 year ago

A user who had two hair transplants and is still concerned about their crown area, despite other people reassuring them that it looks normal. The advice given was to use Minoxidil, Finasteride, SMP, and to consider speaking with a therapist.

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