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    Glossary p38 MAPK

    enzyme involved in cellular stress and inflammation responses

    p38 MAPK, or p38 mitogen-activated protein kinase, is an enzyme that plays a crucial role in cellular responses to stress and inflammation. It is part of a signaling pathway that helps cells react to various external stimuli, such as UV radiation, heat shock, and cytokines, by regulating the expression of specific genes involved in inflammation, cell differentiation, and apoptosis (programmed cell death). This pathway is significant in various biological processes and diseases, including cancer, cardiovascular diseases, and inflammatory conditions.

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    1. Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways Frontiers in Microbiology · 2021 · 30 citations
    2. Sinapic Acid Promotes Browning of 3T3‐L1 Adipocytes via p38 MAPK/CREB Pathway BioMed Research International · 2020 · 29 citations
    3. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    4. Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway Drug Design Development and Therapy · 2025
    5. Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis Scientific Reports · 2026
    6. Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways Molecules · 2026
    7. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    8. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons Chemosphere · 2017 · 10 citations
    9. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    10. Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo Aging · 2022 · 6 citations
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