Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons

    December 2017 in “ Chemosphere
    Yang Yang, Zhaoqing Fang, Yuhua Dai, Yu Wang, Yufeng Liang, Xiaomin Zhong, Qinwen Wang, Yue Hu, Zigui Zhang, Donghong Wu, Xiaoling Xu
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    Studysummary In this study, BPA rapidly increased dendritic spine and synapse densities in cultured rat hippocampal neurons, with involvement of estrogen receptors and ERK1/2 and p38 pathways, but disrupted dihydrotestosterone's effects on synaptic plasticity.
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