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Glossaryc-Jun N-terminal kinase (JNK)

regulates cellular stress responses and apoptosis

c-Jun N-terminal kinase (JNK) is a type of protein kinase that plays a crucial role in regulating various cellular processes, including inflammation, cell growth, and apoptosis (programmed cell death). It is activated in response to stress signals, such as UV radiation or cytokines, and can influence gene expression by modifying the activity of specific transcription factors like c-Jun.

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research Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK-ERK Signaling Pathway

45 citations, April 2013 in “Cell Transplantation”

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation

9 citations, June 2016 in “Stem cells”

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

research Activin B Promotes Epithelial Wound Healing In Vivo Through RhoA-JNK Signaling Pathway

38 citations, September 2011 in “PLOS ONE”

Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.

Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways

research Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways

14 citations, July 2021 in “Biomolecules”

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer

13 citations, September 2019 in “EBioMedicine”

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

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community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 5 months ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.